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<< Tillbaka| Överskrift | A randomised, controlled study on the effects of a short-term endurance training programme in patients with major depression |
|---|---|
| Upplaga | 41(1) |
| Sidor | 29-33 |
| Överskrift | A randomised, controlled study on the effects of a short-term endurance training programme in patients with major depression |
| Beskrivning | OBJECTIVE: To evaluate the short-term effects of exercise in patients with major depression. DESIGN: Prospective, randomised, controlled study. SETTING: A university hospital. PATIENTS: A consecutive series of 38 inpatients with a major depression episode undergoing standard clinical antidepressant drug treatment. INTERVENTIONS: Patients were randomly assigned to an exercise (walking, n = 20) or placebo (low-intensity stretching and relaxation exercises, n = 18) group. Training was carried out for 10 days. Main outcome measurements: Severity of depression assessed with the Bech-Rafaelsen Melancholy Scale (BRMS) and the Center for Epidemiologic Studies Depression scale (CES-D). RESULTS: After 10 days, reduction of depression scores in the exercise group was significantly larger than in the placebo group (BRMS: 36% v 18%; CES-D: 41% v 21%; p for both = 0.01); the proportion of patients with a clinical response (reduction in the BRMS scores by more than six points) was also larger for the exercise group (65% v 22%, p<0.01). CONCLUSIONS: Endurance exercise may help to achieve substantial improvement in the mood of selected patients with major depression in a short time. |
| Källa | Br J Sports Med |
| Publicerad | Epub 2006 |
| Författare | Adli M, Bauer M, Dimeo F, Knubben K, Reischies FM, Schlattmann P |