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Överskrift	Effects of mechanical stretch on collagen type I and total protein synthesis of human periodontal ligament fibroblasts
Upplaga	19(3)
Sidor	155-7
Överskrift	Effects of mechanical stretch on collagen type I and total protein synthesis of human periodontal ligament fibroblasts
Beskrivning	OBJECTIVE: The aim of this study is to investigate the effects of mechanical stretch on type I collagen and total protein synthesis of human periodontal ligament fibroblasts (PDLFs). METHODS: Enzyme link immunosorbent assay (ELISA) and Coomassie brilliant blue stain method were used to examine the anabolism of PDLFs growing on the flexible culture plates subjected to mechanical stretch. The five loading devices of PDLFs were designed and the stain varied from 1% to 8%. RESULTS: Mechanical stretch had no effect on type I collagen synthesis. However, in the range of 1% to 8% of stretch, the protein synthesis was reduced. The mechanical stretching of 2% strain affected the protein synthesis most obviously. CONCLUSION: Mechanical stretch can modify the composition of extracellular matrix of PDLFs.
Källa	Hua Xi Kou Qiang Yi Xue Za Zhi
Publicerad	2001
Författare	Aagaard P, Chen X, Dyhre-Poulsen P, Han W, Kjaer M, Magnusson SP, McHugh MP, Simonsen EB, Zhao Y