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Överskrift A morphological study of the long-term repair process in experimentally stretched but unruptured arteries and veins.
Upplaga 49(1)
Sidor 34-40
Överskrift A morphological study of the long-term repair process in experimentally stretched but unruptured arteries and veins.
Beskrivning As many avulsion amputations are incomplete and the vessels remain intact, the immediate pathology and long-term repair process (to 3 months post-injury) of experimentally stretched but unruptured rabbit femoral arteries and veins were examined. In stretched arteries, circumferential skip lesions involving endothelium, internal elastic lamina (IEL) and media occurred frequently and often up to 3 cm from the point of stretch. Medial smooth muscle cells (SMC) were significantly damaged or lost at lesions. Macrophages and neutrophils were found in lesions 1-4 days post-injury. Between 2-4 days, lesions were covered by endothelium and synthetic state SMC appeared in the media. At 1 week, a thin neointima (which persisted to 3 months) covered many lesions. The media at lesions gradually filled with SMC but generally remained disorganised even at 3 months post-injury. Stretching caused tears in vein walls, particularly close to the point of injury. There was no evidence of venous damage or repair in specimens examined 3 weeks and 3 months post-injury.
Källa Br J Plast Surg,
Publicerad 1996 Jan
Författare Hickey MJ, Kahan BS, McCann JJ, Mitchell GM, Morrison WA, O'Brien BM, Rogers IW, Thomas AD, Wainapel SF

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